Chromosomal Aberrations in Turkish Infertile Couples with Reproductive Problems

The patients included in this study were retrospectively evaluated females and males, who possess a risk for infertility. Over the past 15 years in our laboratory, postnatal karyotyping was done in 160 couples and 210 individuals with unexplained infertility (total 530 infertile cases). The mean age of the women was 32 years (range 19–40), and that of the men was 36 years (range 26–60 years). The sex ratio (male/female) of the patients was 1.1. In control group (the healthy individuals with no reproductive problems), the mean age of the women was 34 years (range 19–45), and that of the men was 38 years (range 26–65 years). The sex ratio (male/female) of the patients was 1.1. The patients were recruited during the year 2003 from the Department of Obstetrics and Gynecology and the Departments of Urology, who postnatally possess a risk for infertility. The genetics diagnosis of the patients is made on the basis of a chromosomal analysis in Department of Medical Biology and Genetics, Faculty of Medicine, Çukurova University. The decision of the ethics committee is not necessary because the patients were sent for diagnosis by the clinicals. Metaphase chromosome preparations from peripheral blood were made according to the standard cytogenetic protocols. Fifty metaphases were analyzed in all the patients, but in cases Introduction